Liver specialists

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Publications

Sigfridsson K, Skantze U, Skantze P, Johansson S, Grant I, Smedsrød B, Britt Fuglesteg B, Elvevold K , Lindfors L. Nanocrystal formulations of a poorly soluble drug. 1. In vitro characterization of stability, stabilizer adsorption and uptake in liver cells. Int. J. Pharm., 2017, 518:29-40.

Sigfridsson K, Skantze P, Skantze U, Svensson L, Löfgren L, Michaëlsson E, Nordell P, Johansson S, Grant I, Smedsrød B, Elvevold K, Lindfors L.  Nanocrystal formulations of a poorly soluble drug. 2. Evaluation of nanocrystal liver uptake and distribution after intravenous administration to mice. Int. J. Pharm., 2017, 524:248-56.

Godfrey C, Lourdes D, Smedsrød B, France P-R, Denti M, Disterer P, Lorain S, Nogales-Gadea G, Sardone V, Rayan A, EL-Andaloussi S, Lehto T, Khoo B, Hjortkjær C, van Roon-Mom W, Goyenvalle A, Aartsma-Rus A, Arechavala-Gomeza V. Delivery is key: lessons learnt from developing splice switching antisense therapies. EMBO Mol Med. 2017, DOI 10.15252/emmm.201607199.

Øie CI, Snapkov I, Elvevold K, Sveinbjørnsson B, Smedsrød B (2016) FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides. PLoS ONE 11(8): e0160602. doi:10.1371/journal.pone.0160602

Sørensen KK, Simon-Santamaria J, McCuskey RS, Smedsrød B. Liver Sinusoidal Endothelial Cells. Compr. Physiol. 2015, 5:1751-74.

Simon-Santamaria J, Rinaldo CH, Kardas P, Li R, Malovic I, Elvevold K, McCourt P, Smedsrød B, Hirsch HH, Sørensen KK. Efficient uptake of blood-borne BK and JC polyomavirus-like particles in endothelial cells of liver sinusoids and renal vasa recta. Plos One 2014, 9:e111762.

Sorensen KK, McCourt P, Berg T, Crossley C, Le Couteur DG, Wake K, Smedsrod B. The scavenger endothelial cell: a new player in homeostasis and immunity. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2012, 303:R1217-30.

Elvevold K, Simon-Santamaria J, Hasvold H, McCourt P, Smedsrød B, Sørensen KK. Liver sinusoidal endothelial cells depend on mannose receptor mediated recruitment of lysosomal enzymes for normal degradation capacity. Hepatology. 2008, 48: 2007-15.

Øie CI, Olsen R, Smedsrod B, Hansen JB. Liver sinusoidal endothelial cells are the principal site for elimination of unfractionated heparin from the circulation. Am. J. Physiol. Gastrointest. Liver Physiol. 2008, 294:G520-8.

Smedsrød B, Einarsson M. Clearance of tissue plasminogen activator by mannose and galactose receptors in liver. Thromb. Haemostas. 1990, 63:60-6.

Smedsrød B, Eriksson S, Fraser JR. Properties of liver endothelial cells in primary monolayer cultures. In: Sinusoidal Liver Cells (eds.: D. L. Knook & E. Wisse) 1982, pp. 263-70, Elsevier Biomedical Press.