Identification of intact LSEC

D'Liver offers fluorescently labelled formaldehyde-treated serum albumin (FITC-FSA) for specific identification of functionally intact LSEC, and for determination of LSEC purity. LSEC is the only cell type that expresses receptors for efficient uptake of FITC-FSA. When low concentrations of FITC-FSA are administered to a mixture of liver cells, the LSEC can easily be identified by their specific uptake of this fluorescent probe. 

FITC-FSA produced by D'Liver is of high quality and guarantees good activity and reproducibility. 

Our FITC-FSA probes are shipped in sealed tubes (1 mg/ml in PBS)

- For research use only -

References:

Isolation of periportal, midlobular, and centrilobular rat liver sinusoidal endothelial cells enables study of zonated drug toxicity

Xie G, Wang L, Wang X, Wang L, DeLeve LD.
Am J Physiol Gastrointest Liver Physiol. 2010 Nov; 299(5): G1204–G1210. 

Liver sinusoidal endothelial cell function in rejected and spontaneously accepted rat liver allografts.

Ge X, Nowak G, Ericzon BG, Sumitran-Holgersson S.
Transpl Int. 2008 Jan;21(1):49-56. Epub 2007 Oct 10.